New wild poliovirus isolates reported this week:
AFP cases: 1
Environment: 3
Others: 0
New cVDPV isolates reported this week:
AFP cases: 11
Environment: 0
Others: 0

Summary of new poliovirus cases and positive environmental samples:
Ethiopia: ten cVDPV2 cases
Nigeria: one cVDPV2 case
Pakistan: One WPV1 cases and 3 WPV1 positive environmental samples

Afghanistan: No WPV1 cases and no WPV1 positive environmental samples were reported this past week. There were 25 WPV1 cases reported last year.
Pakistan: One WPV 1 case and 3 WPV1 positive environmental samples were reported this past week. There were six WPV1 cases reported last year.

Officially reported WPV1 and cVDPV cases as of (October 29, 2024):
Wild poliovirus (WPV)
Total global WPV1 cases in 2025: 1
Total global WPV1 cases in 2024: 98
Total global WPV1 cases in 2023: 12
Total global WPV1 cases in 2022: 30
Total global WPV1 cases in 2021: 6
Total global WPV1 cases in 2020: 140
Circulating vaccine-derived poliovirus (cVDPV) cases
Total global cVDPV cases in 2025: 0
Total global cVDPV cases in 2024: 278
Total global cVDPV cases in 2023: 528
Total global cVDPV cases in 2022: 878

Most recently reported WPV1 case: January 7, 2025, in Pakistan.

This past week, U.S. President Donald Trump signed an executive order to withdraw from the World Health Organization (WHO). The WHO is an organization shaped by its 194 members which facilitates global clinical trials, coordinates vaccine development and distribution, and provides funding for disease surveillance programs. The U.S. had been one of the WHO’s largest financial contributors, having provided roughly one-fifth of the WHO’s budget. The decision to withdraw raises concerns about how global health initiatives such as the Global Polio Eradication Initiative will be funded and implemented, particularly in low-income countries which rely on WHO programs for disease control and vaccinations.